Drug-eluting stents: from evidence to policy

Drug-eluting stents are a major breakthrough in cardiology, with the Cypher™ (Cordis Corporation) and Taxus™ (Boston Scientific) stents preventing 60-70% of repeat coronary revascularizations, compared with bare metal stents. Both evidence- and risk-based application of drug-eluting stents is expect...

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Bibliographic Details
Published inExpert review of medical devices Vol. 1; no. 1; pp. 49 - 63
Main Author Marchetti, Monia
Format Journal Article
LanguageEnglish
Published England Informa Healthcare 01.09.2004
Taylor & Francis
Subjects
Blood Vessel Prosthesis
Cardiology
Clinical Trials as Topic
coronary artery disease
coronary stents
cost-effectiveness analysis
Drug Delivery Systems - instrumentation
Drug Delivery Systems - methods
Drug Implants - therapeutic use
drug-eluting stents
Evidence-Based Medicine
Graft Occlusion, Vascular - prevention & control
Guidelines
Hospitals
Immunosuppressive Agents - administration & dosage
medical devices
Patients
Policies
Prosthesis Design
Public Policy
restenosis
Stents
Strategy
Surgical implants
Treatment Outcome
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Summary:Drug-eluting stents are a major breakthrough in cardiology, with the Cypher™ (Cordis Corporation) and Taxus™ (Boston Scientific) stents preventing 60-70% of repeat coronary revascularizations, compared with bare metal stents. Both evidence- and risk-based application of drug-eluting stents is expected to create relevant financial and equity problems to most public hospitals, as the cost of drug-eluting stents is over €1000 higher than traditional stents. In the perspective of third-party payers, drug-eluting stents are cost-effective revascularization strategies for a large portion of patients actually undergoing stenting. However, adequate guidelines and reimbursement strategies are still awaited in several countries.
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ISSN:1743-4440
1745-2422
DOI:10.1586/17434440.1.1.49