N-Heterocyclic Carbene-Catalyzed Cyclization of Unsaturated Acyl Chlorides and Ketones
A straightforward synthesis of optically active trifluoromethyl dihydropyranones and spirocyclic oxindole‐dihydropyranones has been realized by the chiral N‐heterocyclic carbenes‐catalyzed cyclization of α,β‐unsaturated β‐methylacyl chlorides with activated trifluoromethyl ketones or isatin derivati...
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Published in | Advanced synthesis & catalysis Vol. 353; no. 11-12; pp. 1943 - 1948 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Weinheim
WILEY-VCH Verlag
01.08.2011
WILEY‐VCH Verlag Wiley Wiley-VCH |
Subjects | |
Online Access | Get full text |
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Summary: | A straightforward synthesis of optically active trifluoromethyl dihydropyranones and spirocyclic oxindole‐dihydropyranones has been realized by the chiral N‐heterocyclic carbenes‐catalyzed cyclization of α,β‐unsaturated β‐methylacyl chlorides with activated trifluoromethyl ketones or isatin derivatives. |
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Bibliography: | Chinese Academy of Sciences ark:/67375/WNG-X8N6K70P-5 istex:50842B9CDC029142BAC6D9CCC88D76F800A8C8EA National Natural Science Foundation of China - No. 20872143, 20932008 ArticleID:ADSC201100178 Ministry of Science and Technology of China - No. 2011CB808600 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 |
ISSN: | 1615-4150 1615-4169 1615-4169 |
DOI: | 10.1002/adsc.201100178 |