Sweat gland hamartoma resembling human syringocystadenoma papilliferum in two young cats

Syringocystadenoma papilliferum, a hamartoma with mostly sweat gland, but also follicular infundibular elements, is described on the flank and head of two young cats. Clinically, lesions were cutaneous plaques characterized by irregular but sharply demarcated borders and a roughened, hyperpigmented...

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Published inVeterinary dermatology Vol. 18; no. 6; pp. 451 - 455
Main Authors Heimann, Marianne Hélène, Ngendahayo, Placide
Format Journal Article
LanguageEnglish
Published Oxford, UK Oxford, UK : Blackwell Publishing Ltd 01.12.2007
Blackwell Publishing Ltd
Subjects
adenoma
animal pathology
Animals
case studies
cat diseases
Cat Diseases - diagnosis
Cat Diseases - pathology
Cats
cell proliferation
Cystadenoma, Papillary - diagnosis
Cystadenoma, Papillary - veterinary
Diagnosis, Differential
disease course
epithelium
excision
Female
hamartoma
Hamartoma - diagnosis
Hamartoma - veterinary
head
histopathology
human diseases
Male
signs and symptoms (animals and humans)
skin diseases
skin glands
species differences
Sweat Gland Neoplasms - diagnosis
Sweat Gland Neoplasms - veterinary
sweat glands
syringocystadenoma papilliferum
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Summary:Syringocystadenoma papilliferum, a hamartoma with mostly sweat gland, but also follicular infundibular elements, is described on the flank and head of two young cats. Clinically, lesions were cutaneous plaques characterized by irregular but sharply demarcated borders and a roughened, hyperpigmented surface. Complete surgical excision in one case was curative. Histologically, the lesion was limited to the superficial dermis and consisted of coalescing units of proliferating sweat glands. The proliferation was tubular or papillary, and may have been epitrichial, opening within dilated hypertrophied follicular infundibuli, or atrichial. Three types of epithelium were observed, recapitulating the formation of the follicular-sweat gland unit with infundibular, ductal and secretory epithelia. The glands reacted positively for alpha cytokeratin 8 and were supported by fibrous tissue with a plasmacytic, lymphocytic and neutrophilic infiltrate. As in humans, this lesion may be classified within the hamartoma-nevus-type category.
Bibliography:http://dx.doi.org/10.1111/j.1365-3164.2007.00628.x
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ISSN:0959-4493
1365-3164
DOI:10.1111/j.1365-3164.2007.00628.x