MULUNDOCANDIN, A NEW LIPOPEPTIDE ANTIBIOTIC I. TAXONOMY, FERMENTATION, ISOLATION AND CHARACTERIZATION

• Published in: Journal of antibiotics Vol. 40; no. 3; pp. 275 - 280
• Main Authors: ROY, KIRITY, MUKHOPADHYAY, TRIPTIKUMAR, REDDY, G. C. S., DESIKAN, K. R., GANGULI, B. N.
• Format: Journal Article
• Language: English
• Published: Tokyo JAPAN ANTIBIOTICS RESEARCH ASSOCIATION 1987; Japan Antibiotics Research Association
• Subjects: Antibiotics; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antifungal Agents - isolation & purification; Antifungal Agents - pharmacology; Aspergillus - metabolism; Biological and medical sciences; Biotechnology; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Echinocandins; Fermentation; Fundamental and applied biological sciences. Psychology; Health. Pharmaceutical industry; Industrial applications and implications. Economical aspects; Magnetic Resonance Spectroscopy; Medical sciences; Microbial Sensitivity Tests; Miscellaneous. Antibiotics with multiple activities; Peptides, Cyclic - isolation & purification; Peptides, Cyclic - pharmacology; Pharmacology. Drug treatments; Production of active biomolecules; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Fungi; Antibiotic; Antifungal agent; Taxonomy; Production; Isolation; Fermentation; Biological activity; Physicochemical properties; Thallophyta
• ISSN: 0021-8820; 1881-1469
• DOI: 10.7164/antibiotics.40.275

Mulundocandin, a new lipopeptide antibiotic, was isolated from the culture broth of a strain of Aspergillus sydowi No. Y-30462. The antibiotic, obtained as a colorless amorphous powder having the molecular formula C48H77N7O16, is an antifungal antibiotic active against yeasts and filamentous fungi.