Tumour location is a prognostic factor for survival in colonic cancer patients
Objective To evaluate survival and prognostic factors in a consecutive series of colon cancer patients from a defined city population in Norway. Method All patients with adenocarcinoma of the colon diagnosed between 1993 and 2000 were registered prospectively. Five‐year actuarial survival and 5‐ye...
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Published in | Colorectal disease Vol. 10; no. 1; pp. 33 - 40 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Oxford, UK
Blackwell Publishing Ltd
01.01.2008
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Subjects | |
Online Access | Get full text |
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Summary: | Objective To evaluate survival and prognostic factors in a consecutive series of colon cancer patients from a defined city population in Norway.
Method All patients with adenocarcinoma of the colon diagnosed between 1993 and 2000 were registered prospectively. Five‐year actuarial survival and 5‐year relative survival rates were calculated. Cox regression analyses were used to study the effect of prognostic factors on survival.
Results In the study period 627 patients were admitted. Overall 5‐year relative survival was 50% in females and 52% in males. Five‐year relative survival in 410 (65%) patients operated with curative intent, was 74% for females and 79% for males. Tumour location in the transverse colon, splenic flexure and descending colon (OR = 1.8), emergency operation (OR = 1.7), TNM stage (OR = 1.8–2.9), blood transfusion of more than two units (OR = 1.8) and age (OR = 4.0–7.1) were independent negative prognostic factors.
Conclusion Colon cancer located in the transverse and descending colon is associated with poor prognosis. Comparison of results from different centres is difficult due to selection and classification differences, and different methods used for calculation of survival. |
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Bibliography: | ark:/67375/WNG-DZH9415Q-B ArticleID:CODI1302 istex:EDC6EC3BA27EBF33732CAA9B22B25DFBE4A44EF0 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 1462-8910 1463-1318 |
DOI: | 10.1111/j.1463-1318.2007.01302.x |