A-kinase anchoring proteins that regulate cardiac remodeling

• Published in: Journal of cardiovascular pharmacology Vol. 58; no. 5; p. 451
• Main Authors: Carnegie, Graeme K, Burmeister, Brian T
• Format: Journal Article
• Language: English
• Published: United States 01.11.2011
• Subjects: A Kinase Anchor Proteins - physiology; Animals; Cardiomegaly - metabolism; Excitation Contraction Coupling - physiology; Humans; Sarcomeres - metabolism; Ventricular Remodeling - physiology

In response to injury or stress, the adult heart undergoes maladaptive changes, collectively defined as pathological cardiac remodeling. Here, we focus on the role of A-kinase anchoring proteins (AKAPs) in 3 main areas associated with cardiac remodeling and the progression of heart failure: excitati...