Acute Dystonia in a Patient with 22q11.2 Deletion Syndrome
The 22q11.2 deletion syndrome (di George syndrome) is one of the most prevalent genetic disorders. The clinical features of the syndrome are distinct facial appearance, velopharyngeal insufficiency, conotruncal heart disease, parathyroid and immune dysfunction; however, little is known about possibl...
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Published in | Mental illness Vol. 7; no. 2; p. 5902 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Italy
PAGEPress Publications, Pavia, Italy
30.09.2015
Wiley |
Subjects | |
Online Access | Get full text |
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Summary: | The 22q11.2 deletion syndrome (di George syndrome) is one of the most prevalent genetic disorders. The clinical features of the syndrome are distinct facial appearance, velopharyngeal insufficiency, conotruncal heart disease, parathyroid and immune dysfunction; however, little is known about possible neurodegenerative diseases. We describe the case of an 18-year old patient suffering from 22q11.2 deletion syndrome. Since adolescence, he presented with behavioral disorders, recommended treatment with 2 mg aloperidin and he presented cervical dystonia and emergence of torticollis and trunk dystonia. Antipsychotic medications either accelerate or reveal dystonic symptoms. |
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Bibliography: | Conflict of interest: the authors declare no potential conflict of interest. Contributions: KK designed the study and wrote the first draft of the manuscript; AM and author MM also contributed to the first draft of the manuscript; ST managed the literature searches of the manuscript; CCP had the overall supervision and corrected the final draft. |
ISSN: | 2036-7457 2036-7465 |
DOI: | 10.4081/mi.2015.5902 |