Skin manifestations of COVID-19: A worldwide review
Because of the increasing emergence of skin manifestations of COVID-19 worldwide, we investigated the published reports of these lesions. We conducted a literature search for original and review articles published from November 11, 2019 to September 30, 2020. We identified 5 skin lesions common in p...
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Published in | JAAD international Vol. 2; pp. 119 - 133 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
United States
Elsevier Inc
01.03.2021
Elsevier |
Subjects | |
Online Access | Get full text |
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Summary: | Because of the increasing emergence of skin manifestations of COVID-19 worldwide, we investigated the published reports of these lesions.
We conducted a literature search for original and review articles published from November 11, 2019 to September 30, 2020.
We identified 5 skin lesions common in patients with COVID-19: pseudo-chilblains, rashes containing macules and papules, and urticarial, vesicular, and vaso-occlusive lesions. These lesions manifested at various times in relation to the COVID-19 symptoms, which may indicate whether the lesions are virus-induced or are delayed immunological responses to the infection. Skin lesions were more prevalent among Europeans and United States residents than among Asians, as was pseudo-chilblain, and the morphology of the skin lesions varied among continents. Pseudo-chilblains were the most common COVID-19 skin manifestation in Europe and the United States, but there was only 1 reported case from Asian populations. Additionally, patients with vaso-occlusive lesions were more likely than those with pseudo-chilblains to be admitted to the intensive care unit and to die.
Different cutaneous manifestations in patients with COVID-19 could reflect a wide spectrum of viral interactions with the skin, though reporting bias may play a role as well. |
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Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 |
ISSN: | 2666-3287 2666-3287 |
DOI: | 10.1016/j.jdin.2020.12.003 |