A case of mucosal leishmaniasis: Mimicking intranasal tumor with perforation of septum

A 79-year-old male suffering from nasal congestion was referred to our hospital. Endoscopic examination revealed a hyperemic mass obstructing the left nasal passage. The lesion's surface was smooth. The findings of imaging studies were consistent with a benign tumor despite the erosion and perf...

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Published inJournal of microbiology, immunology and infection Vol. 49; no. 4; pp. 604 - 607
Main Authors Gul, Hanefi Cem, Tosun, Fuat, Karakas, Ahmet, Koru, Ozgur, Onguru, Onder, Mert, Gurkan, Besirbellioglu, Bulent Ahmet, Eyigun, Can Polat
Format Journal Article
LanguageEnglish
Published England Elsevier B.V 01.08.2016
Subjects
Aged
Diagnosis, Differential
Humans
Infectious Disease
Leishmania
Leishmania - isolation & purification
Leishmaniasis
Leishmaniasis - diagnosis
Leishmaniasis - surgery
Male
Medical Education
Mucosal involvement
Nasal Obstruction - diagnosis
Nasal Obstruction - surgery
Nasal Septal Perforation - diagnosis
Nose Neoplasms - diagnosis
Polymerase Chain Reaction
Septal perforation
Turkey
Turkey
Leishmaniasis
Leishmania
Mucosal involvement
Septal perforation
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Summary:A 79-year-old male suffering from nasal congestion was referred to our hospital. Endoscopic examination revealed a hyperemic mass obstructing the left nasal passage. The lesion's surface was smooth. The findings of imaging studies were consistent with a benign tumor despite the erosion and perforation of the septum. The lesion originated from the middle concha and was attached to it with a thin stalk. It was removed easily by endoscopic resection. Histopathology revealed significant infiltration of mononuclear inflammatory cells, mostly lymphocytes and histiocytes, into the edematous subepithelial connective tissue. High-power magnification showed numerous Leishmania amastigotes in the cytoplasm of the histiocytes. A polymerase chain reaction experiment for Leishmania also confirmed the morphological diagnosis. No relapse was observed in the 12 months after surgery and the patient was doing well.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
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ISSN:1684-1182
1995-9133
DOI:10.1016/j.jmii.2013.11.007