Primary epithelioid angiosarcoma of the lung presenting as pulmonary hemorrhage

• Published in: Human pathology Vol. 28; no. 3; pp. 383 - 385
• Main Authors: Sheppard, M.N, Hansell, D.M, Du Bois, R.M, Nicholson, A.G
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.03.1997; Elsevier
• Subjects: Aged; angiosarcoma; Antigens, CD34 - analysis; Biological and medical sciences; epithelioid angiosarcoma; Epithelioid Cells - pathology; Fatal Outcome; Hemangiosarcoma - chemistry; Hemangiosarcoma - diagnosis; Hemangiosarcoma - pathology; Hemorrhage - diagnosis; Humans; lung; Lung Diseases - diagnosis; Lung Neoplasms - chemistry; Lung Neoplasms - diagnosis; Lung Neoplasms - pathology; Male; Medical sciences; Pneumology; Tomography, X-Ray Computed; Tumors of the respiratory system and mediastinum; lung; angiosarcoma; epithelioid angiosarcoma; Human; Immunohistochemistry; Lung disease; Sarcoma; Respiratory disease; Lung; Cardiovascular disease; Malignant tumor; Angiosarcoma; Hemorrhage; Differential diagnostic; Vascular disease; Case study; Pathology; Hemoptysis; Epithelioid cell
• ISSN: 0046-8177; 1532-8392
• DOI: 10.1016/S0046-8177(97)90140-4

Pulmonary angiosarcomas are usually secondary tumors, and only a few primary cases have been described. We report a unique case of epithelioid angiosarcoma arising in the lungs as a bilateral multinodular infiltrate and presenting as pulmonary hemorrhage. Because of its epithelloid histology, this tumor may resemble a carcinoma, also staining positively for keratin markers. Therefore, unless the diagnosis of epithelioid angiosarcoma is considered and endothelial markers used, the diagnosis of epithelloid angiosarcoma may be overlooked at this site.