Self-collected mid-nasal swabs and saliva specimens, compared with nasopharyngeal swabs, for SARS-CoV-2 detection in mild COVID-19 patients

•Self-collected nasal and saliva samples can be used for SARS-CoV-2 screening.•Self-collected nasal and saliva specimens had a 99% and 90% sensitivity, respectively.•Nasopharyngeal swab viral loads correlate better with nasal than saliva.•Viral load correlations are poorer at day 7, when lower viral...

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Published inThe Journal of infection Vol. 83; no. 6; pp. 709 - 737
Main Authors Alemany, Andrea, Millat-Martinez, Pere, Ouchi, Dan, Corbacho-Monné, Marc, Bordoy, Antoni E., Esteban, Cristina, Hernández, Águeda, Casañ, Cristina, Gonzalez, Victoria, Costes, Gèlia, Capdevila-Jáuregui, Mar, Torrano-Soler, Pamela, San José, Alba, Ara, Jordi, Prat, Núria, Clotet, Bonaventura, Bassat, Quique, Gimenez, Montserrat, Blanco, Ignacio, Baro, Bàrbara, Mitjà, Oriol
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.12.2021
The British Infection Association. Published by Elsevier Ltd
Subjects
COVID-19
Diagnostic Tests, Routine
Humans
Letter to the Editor
Nasal
Nasopharyngeal swab
Nasopharynx
RNA, Viral
Saliva
SARS-CoV-2
Screening
Specimen Handling
Viral load
Nasopharyngeal swab
Screening
SARS-CoV-2
Nasal
Saliva
Viral load
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Summary:•Self-collected nasal and saliva samples can be used for SARS-CoV-2 screening.•Self-collected nasal and saliva specimens had a 99% and 90% sensitivity, respectively.•Nasopharyngeal swab viral loads correlate better with nasal than saliva.•Viral load correlations are poorer at day 7, when lower viral loads are observed.
Bibliography:SourceType-Other Sources-1
ObjectType-Article-2
content type line 63
ObjectType-Correspondence-1
These authors contributed equally to this work.
ISSN:0163-4453
1532-2742
DOI:10.1016/j.jinf.2021.09.012