Circadian Blood Pressure Rhythm in Cardiovascular and Renal Health and Disease

Blood pressure (BP) follows a circadian rhythm, it increases on waking in the morning and decreases during sleeping at night. Disruption of the circadian BP rhythm has been reported to be associated with worsened cardiovascular and renal outcomes, however the underlying molecular mechanisms are stil...

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Published inBiomolecules (Basel, Switzerland) Vol. 11; no. 6; p. 868
Main Authors Zhang, Jiayang, Sun, Ruoyu, Jiang, Tingting, Yang, Guangrui, Chen, Lihong
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 11.06.2021
MDPI
Subjects
Blood pressure
cardiovascular
Circadian rhythm
Circadian rhythms
Genes
Genetic engineering
Homeostasis
Hormones
Hypertension
Kinases
Melatonin
Molecular modelling
Regulation
renal
Review
Rodents
Sleep
Smooth muscle
Sodium
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Summary:Blood pressure (BP) follows a circadian rhythm, it increases on waking in the morning and decreases during sleeping at night. Disruption of the circadian BP rhythm has been reported to be associated with worsened cardiovascular and renal outcomes, however the underlying molecular mechanisms are still not clear. In this review, we briefly summarized the current understanding of the circadian BP regulation and provided therapeutic overview of the relationship between circadian BP rhythm and cardiovascular and renal health and disease.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:2218-273X
2218-273X
DOI:10.3390/biom11060868