Prevalence of latent tuberculosis and treatment adherence among patients with chronic kidney disease in Campo Grande, State of Mato Grosso do Sul

• Published in: Revista da Sociedade Brasileira de Medicina Tropical Vol. 47; no. 2; pp. 204 - 211
• Main Authors: Chagas, Aucely Corrêa Fernandes, Hans Filho, Günter, de Oliveira, Sandra Maria do Valle Leone, Ivo, Maria Lúcia, Corrêa Filho, Ruy Alberto Caetano, Donatti, Maria Ilizabeth
• Format: Journal Article
• Language: English; Portuguese
• Published: Brazil Sociedade Brasileira de Medicina Tropical - SBMT 01.04.2014; Sociedade Brasileira de Medicina Tropical (SBMT)
• Subjects: Adult; Aged; Brazil - epidemiology; Chronic kidney disease; Female; Humans; Latent tuberculosis; Latent Tuberculosis - complications; Latent Tuberculosis - diagnosis; Latent Tuberculosis - drug therapy; Latent Tuberculosis - epidemiology; Male; Middle Aged; Patient Compliance - statistics & numerical data; Prevalence; Renal Dialysis; Renal Insufficiency, Chronic - complications; Renal Insufficiency, Chronic - therapy; Socioeconomic Factors; TROPICAL MEDICINE; Tuberculin skin test; Tuberculin Test; Young Adult; Brazil; Latent tuberculosis; Renal dialysis; Chronic kidney disease; Prevalence; Tuberculin skin test
• ISSN: 0037-8682; 1678-9849; 1678-9849; 0037-8682
• DOI: 10.1590/0037-8682-0035-2014

The primary strategy for tuberculosis control involves identifying individuals with latent tuberculosis. This study aimed to estimate the prevalence of latent tuberculosis in chronic kidney disease (CKD) patients who were undergoing hemodialysis in Campo Grande, State of Mato Grosso do Sul, Brazil, to characterize the sociodemographic and clinical profiles of patients with latent tuberculosis, to verify the association between sociodemographic and clinical characteristics and the occurrence of latent tuberculosis, and to monitor patient adherence to latent tuberculosis treatment. This epidemiological study involved 418 CKD patients who were undergoing hemodialysis and who underwent a tuberculin skin test. The prevalence of latent tuberculosis was 10.3%. The mean patient age was 53.43±14.97 years, and the patients were predominantly men (63.9%). The population was primarily Caucasian (58.6%); half (50%) were married, and 49.8% had incomplete primary educations. Previous contact with tuberculosis patients was reported by 80% of the participants. Treatment adherence was 97.7%. We conclude that the prevalence of latent tuberculosis in our study population was low. Previous contact with patients with active tuberculosis increased the occurrence of latent infection. Although treatment adherence was high in this study, it is crucial to monitor tuberculosis treatment administered to patients in health services to maintain this high rate.