Long-term non-invasive ventilation therapies in children: a scoping review

• Published in: Sleep medicine reviews Vol. 37; pp. 148 - 158
• Main Authors: Castro-Codesal, Maria L, Dehaan, Kristie, Featherstone, Robin, Bedi, Prabhjot K, Martinez Carrasco, Carmen, Katz, Sherri L, Chan, Elaine Y, Bendiak, Glenda N, Almeida, Fernanda R, Olmstead, Deborah, Young, Rochelle, Woolf, Vicki, Waters, Karen A, Sullivan, Collin, Hartling, Lisa, MacLean, Joanna E
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.02.2018
• Subjects: Artificial respiration; Child; Continuous positive airway pressure; Continuous Positive Airway Pressure - methods; Humans; Neurology; Noninvasive Ventilation - methods; Pediatrics; Respiratory insufficiency; Respiratory Insufficiency - etiology; Respiratory Insufficiency - therapy; Scoping review; Sleep apnea; Sleep Apnea, Obstructive - etiology; Sleep Apnea, Obstructive - therapy; Sleep Medicine; Time Factors; Pediatrics; Sleep apnea; Respiratory insufficiency; Continuous positive airway pressure; Artificial respiration; scoping review; Scoping review
• ISSN: 1087-0792; 1532-2955
• DOI: 10.1016/j.smrv.2017.02.005

Summary Long-term non-invasive ventilation (NIV) is a common modality of breathing support used for a range of sleep and respiratory disorders. The aim of this scoping review was to provide a summary of the literature relevant to long-term NIV use in children. We used systematic methodology to identify 11581 studies with final inclusion of 289. We identified 76 terms referring to NIV; the most common term was NIV (22%). Study design characteristics were most often single center (84%), observational (63%), and retrospective (54%). NIV use was reported for 73 medical conditions with obstructive sleep apnea and spinal muscular atrophy as the most common conditions. Descriptive data, including NIV incidence (61%) and patient characteristics (51%), were most commonly reported. Outcomes from sleep studies were reported in 27% of studies followed by outcomes on respiratory morbidity reduction in 19%. Adverse events and adherence were reported in 20% and 26% of articles respectively. Authors reported positive conclusions for 73% of articles. Long-term use of NIV has been documented in a large variety of pediatric patient groups with studies of lower methodological quality. While there is considerable data for the most common conditions, there is less data to support NIV use for many additional conditions.