Histopathological findings of an uncommon co-infection: Echinococcus vogeli , HIV, hepatitis C virus, and hepatitis B virus

Summary Our work represents the first case report of polycystic echinococcosis co-infection with HIV, hepatitis C virus (HCV), and hepatitis B virus (HBV). Structural liver alterations were found to be related to parasitic structures and necroinflammatory foci (karyopyknosis, karyorrhexis, and karyo...

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Bibliographic Details
Published inInternational journal of infectious diseases Vol. 17; no. 10; pp. e925 - e927
Main Authors de Almeida, Fernanda Barbosa, Corrêa, Christiane Leal, de Siqueira, Nilton Ghiotti, de Carvalho, Nellysie Virgínia F.M. dos S. Castro, Rodrigues-Silva, Rosângela, de Andrade, Arnaldo Feitosa B, Machado-Silva, José Roberto
Format Journal Article
LanguageEnglish
Published Canada Elsevier Ltd 01.10.2013
Subjects
Albendazole - therapeutic use
Anti-HIV Agents - therapeutic use
Anticestodal Agents - therapeutic use
Antiretroviral Therapy, Highly Active
Co-infection
Coinfection - drug therapy
Coinfection - pathology
Echinococcosis - drug therapy
Echinococcosis - pathology
Female
HBV
HCV
Hepatitis B - pathology
Hepatitis C - pathology
HIV
HIV Infections - drug therapy
HIV Infections - pathology
Humans
Infectious Disease
Liver - parasitology
Liver - pathology
Middle Aged
Polycystic echinococcosis
Pulmonary/Respiratory
Treatment Outcome
HCV
Co-infection
HIV
Polycystic echinococcosis
HBV
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Summary:Summary Our work represents the first case report of polycystic echinococcosis co-infection with HIV, hepatitis C virus (HCV), and hepatitis B virus (HBV). Structural liver alterations were found to be related to parasitic structures and necroinflammatory foci (karyopyknosis, karyorrhexis, and karyolysis), consistent with Echinococcus vogeli . Visceral adipose tissue and intrahepatic triglyceride droplets (macrovesicular and microvesicular steatosis) indicated abnormal fat anabolism, which probably resulted from both viral-induced hepatopathy and drug-related toxicity. In summary, our results suggest that the observed liver abnormalities reflected the coincident exposure to hepatotropic viruses and parasites causing polycystic echinococcosis and were not indicative of opportunistic relationships among these pathogens.
ISSN:1201-9712
1878-3511
DOI:10.1016/j.ijid.2013.04.002