Early seasonal coronavirus seroconversion did not produce cross-protective SARS-CoV-2 antibodies

•Seropositivity to endemic human coronaviruses (HCoV) differs by age.•Seropositivity rises in early life, increases in adolescence; declines in adulthood.•No cross neutralization of SARS-CoV-2 despite high seropositivity to endemic HCoV. [Display omitted]

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Bibliographic Details
Published inThe Journal of infection Vol. 86; no. 1; pp. e10 - e12
Main Authors Wong, Lydia Su Yin, Loo, Evelyn Xiu Ling, Huang, Chiung-Hui, Yap, Gaik Chin, Tay, Michelle Jia Yu, Chua, Regena Xin Yi, Kang, Alicia Yi Hui, Lu, Liangjian, Lee, Bee Wah, Shek, Lynette Pei-Chi, Zhang, Jinyan, Chia, Wan Ni, Wang, Lin-Fa, Tham, Elizabeth Huiwen, Tambyah, Paul Anantharajah
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.01.2023
The British Infection Association. Published by Elsevier Ltd
Subjects
Antibodies
Antibodies, Neutralizing
Antibodies, Viral
Coronavirus
COVID-19
Cross-neutralization
Humans
Letter to the Editor
SARS-CoV-2
Seasons
Seroconversion
Seroepidemiologic Studies
Seroprevalence
Spike Glycoprotein, Coronavirus
Antibodies
Coronavirus
HCoV
Cross-neutralization
Seroconversion
Seroprevalence
Online AccessGet full text

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Summary:•Seropositivity to endemic human coronaviruses (HCoV) differs by age.•Seropositivity rises in early life, increases in adolescence; declines in adulthood.•No cross neutralization of SARS-CoV-2 despite high seropositivity to endemic HCoV. [Display omitted]
Bibliography:SourceType-Other Sources-1
content type line 63
ObjectType-Correspondence-1
ObjectType-Commentary-2
ObjectType-Article-3
ISSN:0163-4453
1532-2742
DOI:10.1016/j.jinf.2022.08.032