Periampullary diverticula causing pancreaticobiliary disease

• Published in: Digestive diseases and sciences Vol. 49; no. 11-12; pp. 1943 - 1945
• Main Authors: YILDIRGAN, M. Ilhan, BASOGLU, Mahmut, YILMAZ, Ismayil, ATAMANALP, S. Selcuk, BALIK, Ahmet A, AYDINLI, Bülent, ÖZTÜRK, Gürkan
• Format: Journal Article
• Language: English
• Published: Heidelberg Springer 01.11.2004; Springer Nature B.V
• Subjects: Ampulla of Vater; Bacterial diseases; Bacterial diseases of the digestive system and abdomen; Biliary Tract Diseases - etiology; Biological and medical sciences; Cholecystectomy; Diverticulum - complications; Duodenal Diseases - complications; Duodenum - anatomy & histology; Duodenum - pathology; Gastroenterology. Liver. Pancreas. Abdomen; Human bacterial diseases; Humans; Infectious diseases; Liver. Biliary tract. Portal circulation. Exocrine pancreas; Medical sciences; Other diseases. Semiology; Pancreatic Diseases - etiology; acute cholangitis; periampullary diverticula; Duodenum; duodenal diverticula; Acute; Cholangitis; Pancreatitis; Biliary tract disease; Infection; acute pancreatitis; Bacteriosis; Digestive diseases; Periampullary; Pancreatic disease
• ISSN: 0163-2116; 1573-2568
• DOI: 10.1007/s10620-004-9597-9

Our purpose was to determine if the presence of duodenal diverticula predisposes to the development of pancreaticobiliary disease. Between May 1999 and February 2001, 381 patients were examined by endoscopic retrograde cholangiopancreaticography. Of these patients, 51 had periampullary diverticula. In 27 patients the papilla was located inside the diverticulum (Group I), in 19 patients it was located at the edge of the diverticulum (Group II), and 5 patients it was located at a distance closer than 3 cm to the diverticulum (Group III). Seventeen patients in group I and 11 patients in group II had had a previous cholecystectomy. The overall incidence of biliary system stone disease was 22.2% in group I, 36.8% in group II, and 100% in group III. All patients were treated with endoscopic sphincterotomy and three (two in group I and one in group II) developed biliary system disease (cholangitis or pancreatitis). We think that sphincterotomy should be applied regardless of the presence of stone if the papilla is located inside or at the edge of the diverticulum. If the papilla is located 3 cm or more far for diverticulum, it should be considered within the frame of general sphincterotomy indications in the absence of stone disease.