Platelets to surrogate lung inflammation in COVID-19 patients

The neoteric severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been jeopardizing the world with the symptoms of seasonal flu. The virus contagion predicted to have been originated from Wuhan, China has by far trapped 4,198,418 cases from 212 countries in the world with two internation...

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Bibliographic Details
Published inMedical hypotheses Vol. 143; p. 110098
Main Authors Kuchi Bhotla, Haripriya, Kaul, Tanushri, Balasubramanian, Balamuralikrishnan, Easwaran, Murugesh, Arumugam, Vijaya Anand, Pappusamy, Manikantan, Muthupandian, Saravanan, Meyyazhagan, Arun
Format Journal Article
LanguageEnglish
Published United States Elsevier Ltd 01.10.2020
Subjects
Betacoronavirus
Blood Platelets - virology
China
Coronavirus Infections - blood
COVID-19
Cytokines - metabolism
Humans
Inflammation - blood
Inflammation - virology
Letter to Editors
Lung - virology
Lung inflammation
Megakaryocytes - virology
Pandemics
Pathogenesis
Platelets
Pneumonia, Viral - blood
SARS-CoV-2
Thrombocytopenia
China
COVID-19
Thrombocytopenia
Lung inflammation
Platelets
Pathogenesis
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Summary:The neoteric severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been jeopardizing the world with the symptoms of seasonal flu. The virus contagion predicted to have been originated from Wuhan, China has by far trapped 4,198,418 cases from 212 countries in the world with two international conveyances with 284,102 deaths as of 11 May 2020 (10:18 GMT). Researchers around the globe have indulged in deciphering viral mode in the body for devising a cure. Affirmations from autopsies and preliminary findings on SARS-CoV-2 hypothesized on viral pathogenesis within the host, for instance, source of inflammation in lungs and pneumonia. This hypothesis assigns the platelets as agents of infection after viral entry. Presently, curbing infection to stall the spread of SARS-CoV-2 is the prima facie intervention employed, worldwide. However, public health authorities must monitor the state of affairs scrupulously, as the deeper our understanding of this novel virus and its associated outbreak, the better we can deal with it. Knowing this idea might be far-fetched, yet this postulate would serve as the groundwork for the present situation.
Bibliography:SourceType-Other Sources-1
content type line 63
ObjectType-Correspondence-1
Equal contribution as a first author.
ISSN:0306-9877
1532-2777
DOI:10.1016/j.mehy.2020.110098