Voltammetric determination of bisoprolol on a glassy carbon electrode modified by poly(arylene phthalide)

• Published in: Journal of analytical chemistry (New York, N.Y.) Vol. 71; no. 9; pp. 926 - 931
• Main Authors: Zil’berg, R. A., Yarkaeva, Yu. A., Sidel’nikov, A. V., Maistrenko, V. N., Kraikin, V. A., Gileva, N. G.
• Format: Journal Article
• Language: English
• Published: Moscow Pleiades Publishing 01.09.2016; Springer; Springer Nature B.V
• Subjects: Analytical Chemistry; Aromatic compounds; Bisoprolol; Carbon electrodes; Chemical properties; Chemistry; Chemistry and Materials Science; Voltammetry; cyclic voltammetry; square-wave voltammetry; bisoprolol; modified glassy carbon electrodes; poly(arylene phthalide)
• ISSN: 1061-9348; 1608-3199
• DOI: 10.1134/S1061934816090173

New voltammetric sensors based on glassy carbon electrodes (GCEs) modified by poly(arylene phthalide) are studied. The electrochemical behavior of bisoprolol on GCEs modified by poly(arylene phthalide) is investigated. The effects of potential scan rate, time of accumulation on the electrode, pH of supporting electrolyte, and concentration on the current of bisoprolol electrooxidation are estimated. A procedure is developed for the voltammetric determination of bisoprolol on glassy carbon electrodes modified by poly(arylene phthalide). The dependence of the analytical signal on the concentration of bisoprolol is linear in the range 10 –6 –10 –5 M with the limit of detection (3.4–9.8) × 10 –8 M.