Long-Term Isolation Stress in Rats

Rats isolated for long periods became nervous and aggressive and developed caudal dermatitis (scaly tail). After 13 weeks of isolation, rats had heavier adrenals and thyroid and lighter spleen and thymus compared with rats kept in community cages. This indicates an endocrinopathy with hyper-function...

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Published inScience (American Association for the Advancement of Science) Vol. 142; no. 3591; p. 507
Main Authors Hatch, Anita, Balazs, Tibor, Wiberg, G. S., Grice, H. C.
Format Journal Article
LanguageEnglish
Published United States American Association for the Advancement of Science 25.10.1963
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Summary:Rats isolated for long periods became nervous and aggressive and developed caudal dermatitis (scaly tail). After 13 weeks of isolation, rats had heavier adrenals and thyroid and lighter spleen and thymus compared with rats kept in community cages. This indicates an endocrinopathy with hyper-function of the adrenal cortex.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0036-8075
1095-9203
DOI:10.1126/science.142.3591.507