The well-tempered vessel

Although gene therapy studies of angiogenesis have focused on the ability of endothelial cells to form new structures, it has recently become clear that the subsequent stages of remodeling are crucial to attaining stable and functional vessels. A precise balance of cell types and molecules is requir...

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Bibliographic Details
Published inNature medicine Vol. 7; no. 5; pp. 532 - 534
Main Authors Blau, Helen M, Banfi, Andrea
Format Journal Article
LanguageEnglish
Published United States Nature Publishing Group 01.05.2001
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Summary:Although gene therapy studies of angiogenesis have focused on the ability of endothelial cells to form new structures, it has recently become clear that the subsequent stages of remodeling are crucial to attaining stable and functional vessels. A precise balance of cell types and molecules is required for normal vessel maturation and must be considered in the design of therapeutic angiogenic strategies.
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ISSN:1078-8956
1546-170X
DOI:10.1038/87850