Intraventricular hemorrhage in term neonates caused by sinovenous thrombosis

• Published in: Annals of neurology Vol. 54; no. 1; pp. 123 - 126
• Main Authors: Wu, Yvonne W., Hamrick, Shannon E. G., Miller, Steven P., Haward, Marlyse F., Lai, Michael C., Callen, Peter W., Barkovich, A. James, Ferriero, Donna M.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.07.2003; Willey-Liss
• Subjects: Biological and medical sciences; Cerebral Hemorrhage - etiology; Cerebral Hemorrhage - pathology; Cerebral Veins - pathology; Cerebral Ventricles - pathology; Gestational Age; Humans; Infant, Newborn; Magnetic Resonance Imaging; Medical sciences; Neurology; Sinus Thrombosis, Intracranial - complications; Sinus Thrombosis, Intracranial - pathology; Vascular diseases and vascular malformations of the nervous system; Human; Nervous system diseases; Cardiovascular disease; Cerebral ventricle; Thrombosis; Cerebral disorder; Vascular disease; Pregnancy; Newborn; Cerebral hemorrhage; Central nervous system disease; Computerized axial tomography; Cerebrovascular disease
• ISSN: 0364-5134; 1531-8249
• DOI: 10.1002/ana.10619

The cause of intraventricular hemorrhage in term neonates is poorly understood. Among 29 neonates of at least 36 weeks' gestation with intraventricular hemorrhage, 9 (31%) had cerebral sinovenous thrombosis. Of the 26 neonates who underwent computed tomography or magnetic resonance studies, those with thalamic hemorrhage were more likely to have sinovenous thrombosis than those without thalamic involvement (4/5 vs 5/21, p = 0.03). Term neonates with intraventricular hemorrhage should undergo neuroimaging to evaluate the presence of sinovenous thrombosis. Ann Neurol 2003