Aminoglycoside ototoxicity in the neonatal period: possible etiologic factor delayed postural control

Forty-three infants, treated with aminoglycosides during the neonatal period, were tested repeatedly over a period of two to five years for neurovestibular responses. Results of testing were compared with those obtained from a group of 276 healthy newborns followed simultaneously. No abnormalities w...

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Bibliographic Details
Published inOtolaryngology-head and neck surgery Vol. 89; no. 5; p. 818
Main Authors Eviatar, L, Eviatar, A
Format Journal Article
LanguageEnglish
Published England 01.09.1981
Subjects
Aminoglycosides - adverse effects
Aminoglycosides - therapeutic use
Child, Preschool
Cochlea - drug effects
Follow-Up Studies
Hearing Loss, Sensorineural - chemically induced
Humans
Infant
Infant, Newborn
Infant, Newborn, Diseases - drug therapy
Posture
Sepsis - drug therapy
Vestibular Function Tests
Vestibule, Labyrinth - drug effects
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Summary:Forty-three infants, treated with aminoglycosides during the neonatal period, were tested repeatedly over a period of two to five years for neurovestibular responses. Results of testing were compared with those obtained from a group of 276 healthy newborns followed simultaneously. No abnormalities were found in the untreated group. Among the treated infants, three had a sensorineural hearing loss and eight had laboratory evidence of vestibular dysfunction and delay of head and postural control.
ISSN:0194-5998
DOI:10.1177/019459988108900524