Effect of Cinnamoyl and Flavonol Glucosides Derived from Cherry Blossom Flowers on the Production of Advanced Glycation End Products (AGEs) and AGE-induced Fibroblast Apoptosis

• Published in: Phytotherapy research Vol. 25; no. 9; pp. 1328 - 1335
• Main Authors: Shimoda, Hiroshi, Nakamura, Seiko, Morioka, Makoto, Tanaka, Junji, Matsuda, Hisashi, Yoshikawa, Masayuki
• Format: Journal Article
• Language: English
• Published: Chichester, UK John Wiley & Sons, Ltd 01.09.2011; Wiley
• Subjects: advanced glycation end product; Apoptosis - drug effects; Biological and medical sciences; Caffeic Acids - pharmacology; caffeoyl glucose; Cell Line; cherry blossom; Collagen - metabolism; collagen lattice; fibroblast; Fibroblasts - drug effects; Flavonols - pharmacology; Flowers - chemistry; General pharmacology; Glucosides - pharmacology; Glycation End Products, Advanced - metabolism; Humans; Medical sciences; Pharmacognosy. Homeopathy. Health food; Pharmacology. Drug treatments; Plant Extracts - pharmacology; Prunus - chemistry; Quercetin - analogs & derivatives; Quercetin - pharmacology; quercetin glucoside; Glucose; Flavonoid; Medicinal plant; caffeoyl glucose; Polyphenol; Glycoside; Age; advanced glycation end product; Flower; Aldose; Pharmacognosy; Glycoprotein; Glucoside; Protein; collagen lattice; Cell death; Collagen; Cinnamic acid derivatives; Plant origin; Quercetin; Phenols; cherry blossom; Fibroblast; Apoptosis; quercetin glucoside; fibroblast

Cherry blossom flowers are familiar to the Japanese, and some species of the flowers soaked in salty vinegar are used as processed foods. The constituents of aqueous ethanol extract from cherry blossom (Prunus lannesiana) flowers (CBE) were examined and cinnamoyl and flavonol glucosides were isolate...