Post translational modification-assisted cancer immunotherapy for effective breast cancer treatment

• Published in: Chemical science (Cambridge) Vol. 11; no. 38; pp. 1421 - 143
• Main Authors: Theivendran, Shevanuja, Tang, Jie, Lei, Chang, Yang, Yannan, Song, Hao, Gu, Zhengying, Wang, Yue, Yang, Yang, Jin, Lei, Yu, Chengzhong
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 10.09.2020; The Royal Society of Chemistry
• Subjects: Antigens; Breast cancer; Cell death; Chemistry; Customization; Immunotherapy; Lymphocytes; Nanoparticles; Nanotechnology; Phosphorylation; Silicon dioxide; Strategy; Tumors

Post translational modifications (PTM) such as phosphorylation are often correlated with tumorigenesis and malignancy in breast cancer. Herein, we report a PTM-assisted strategy as a simplified version of a personalized cancer vaccine for enhanced cancer immunotherapy. Titanium modified dendritic me...