Streptomyces sudanensis sp. nov., a new pathogen isolated from patients with actinomycetoma

• Published in: Antonie van Leeuwenhoek Vol. 93; no. 3; pp. 305 - 313
• Main Authors: Quintana, Erika T, Wierzbicka, Katarzyna, Mackiewicz, Pawel, Osman, Abdalla, Fahal, Ahmed H, Hamid, Mohamed E, Zakrzewska-Czerwinska, Jolanta, Maldonado, Luis A, Goodfellow, Michael
• Format: Journal Article
• Language: English
• Published: Dordrecht Dordrecht : Springer Netherlands 01.03.2008; Springer Netherlands; Springer; Springer Nature B.V
• Subjects: Actinomycetales Infections - microbiology; Bacteria; Bacteriology; Biological and medical sciences; Biomedical and Life Sciences; Deoxyribonucleic acid; DNA; DNA, Bacterial - genetics; Fundamental and applied biological sciences. Psychology; Genotype & phenotype; Humans; Life Sciences; Medical Microbiology; Microbiology; Molecular Sequence Data; Original Paper; Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains; Phylogeny; Plant Sciences; Ribonucleic acid; RNA; Soil Science & Conservation; Streptomyces; Streptomyces - classification; Streptomyces - genetics; Streptomyces - isolation & purification; Streptomyces somaliensis; Systematics; Streptomyces; Mycetoma; Polyphasic taxonomy; Pseudotumor; Human; Streptomycetaceae; Taxonomy; Actinomycosis; Actinomycetales; Infection; Phenotype; Bacteriosis; Bacteria; Tumor; Actinomycetes; New species; Clinical isolate; Actinomycetoma
• ISSN: 0003-6072; 1572-9699
• DOI: 10.1007/s10482-007-9205-z

Nine strains isolated from mycetoma patients and received as Streptomyces somaliensis were the subject of a polyphasic taxonomic study. The organisms shared chemical markers consistent with their classification in the genus Streptomyces and formed two distinct monophyletic subclades in the Streptomyces 16S rRNA gene tree. The first subclade contained four organisms, including the type strain of S. somaliensis, and the second clade the remaining five strains which had almost identical 16S rRNA sequences. Members of the two subclades were sharply separated using DNA:DNA relatedness and phenotypic data which also showed that the subclade 1 strains formed an heterogeneous group. In contrast, the subclade 2 strains were assigned to a single genomic species and had identical phenotypic profiles. It is evident from these data that the subclade 2 strains should be recognised as a new species of Streptomyces. The name proposed for this new species is Streptomyces sudanensis sp. nov. The type strain is SD 504T (DSM = 41923T = NRRL B-24575T).