Associations of Moderate to Severe Asthma with Obstructive Sleep Apnea

• Published in: Yonsei medical journal Vol. 54; no. 4; pp. 942 - 948
• Main Authors: Byun, Min Kwang, Park, Seon Cheol, Chang, Yoon Soo, Kim, Young Sam, Kim, Se Kyu, Kim, Hyung Jung, Chang, Joon, Ahn, Chul Min, Park, Moo Suk
• Format: Journal Article
• Language: English
• Published: Korea (South) Yonsei University College of Medicine 01.07.2013; 연세대학교의과대학
• Subjects: Aged; Asthma - complications; Asthma - epidemiology; Asthma - etiology; Comorbidity; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Original; Polysomnography - instrumentation; Severity of Illness Index; Sleep Apnea Syndromes - epidemiology; Sleep Apnea Syndromes - etiology; Sleep Apnea, Obstructive - complications; Sleep Apnea, Obstructive - epidemiology; Sleep Apnea, Obstructive - physiopathology; 의학일반; ApneaLink; obstructive sleep apnea; asthma; sleep-disordered breathing; Apnea-hypopnea index
• ISSN: 0513-5796; 1976-2437; 1976-2437
• DOI: 10.3349/ymj.2013.54.4.942

This study aimed to evaluate the correlation between associating factors of moderate to severe asthma with obstructive sleep apnea (OSA). One hundred and sixty-seven patients who visited the pulmonary and sleep clinic in Severance Hospital presenting with symptoms of sleep-disordered breathing were evaluated. All subjects were screened with ApneaLink. Thirty-two subjects with a high likelihood of having OSA were assessed with full polysomnography (PSG). The mean age was 58.8±12.0 years and 58.7% of subjects were male. The mean ApneaLink apnea-hypopnea index (AHI) was 12.7±13.0/hr. The mean ApneaLink AHI for the 32 selected high risk patients of OSA was 22.3±13.2/hr, which was lower than the sleep laboratory-based PSG AHI of 39.1±20.5/hr. When OSA was defined at an ApneaLink AHI≥5/hr, the positive correlating factors for OSA were age, male gender, and moderate to severe asthma. Moderate to severe asthma showed strong correlation with OSA when defined at an ApneaLink AHI≥5/hr.