Embolic Events in Infective Endocarditis: A Comprehensive Review

Infective endocarditis (IE) is a life-threating entity with three main complications: heart failure (HF), uncontrolled infection (UI) and embolic events (EEs). HF and UI are the main indications of cardiac surgery and have been studied thoroughly. On the other hand, much more uncertainty surrounds E...

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Published inReviews in cardiovascular medicine Vol. 25; no. 3; p. 97
Main Authors Cabezon, Gonzalo, Pulido, Paloma, López Díaz, Javier, de Miguel-Álava, María, Vilacosta, Isidre, García-Azorin, David, Lozano, Adrian, Oña, Andrea, Arenillas, Juan Francisco, San Román, José-Alberto
Format Journal Article
LanguageEnglish
Published Singapore IMR Press 01.03.2024
Subjects
embolic events
infective endocarditis
mycotic aneurysm
Review
stroke
infective endocarditis
mycotic aneurysm
stroke
embolic events
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Summary:Infective endocarditis (IE) is a life-threating entity with three main complications: heart failure (HF), uncontrolled infection (UI) and embolic events (EEs). HF and UI are the main indications of cardiac surgery and have been studied thoroughly. On the other hand, much more uncertainty surrounds EEs, which have an abrupt and somewhat unpredictable behaviour. EEs in the setting of IE have unique characteristics that must be explored, such as the potential of hemorrhagic transformation of stroke. Accurately predicting which patients will suffer EEs seems to be pivotal to achieve an optimal management of the disease, but this complex process is still not completely understood. The indication of cardiac surgery in order to prevent EEs in the absence of HF or UI is in question as scientific evidence is controversial and mainly of a retrospective nature. This revision addresses these topics and try to summarize the evidence and recommendations about them.
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These authors contributed equally.
ISSN:1530-6550
2153-8174
2153-8174
1530-6550
DOI:10.31083/j.rcm2503097