Supramolecular optimization of the visual contrast for colorimetric indicator assays that release resorufin dye

A tetralactam macrocycle acts as a novel supramolecular adjuvant to capture a released resorufin dye and create a higher contrasting yellow/blue color change for enhanced naked eye interpretation of a colorimetric indicator assay. A tetralactam macrocycle captures released resorufin and creates a pa...

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Published inChemical communications (Cambridge, England) Vol. 56; no. 65; pp. 9296 - 9299
Main Authors Morsby, Janeala J, Dharmarwardana, Madushani, McGarraugh, Hannah, Smith, Bradley D
Format Journal Article
LanguageEnglish
Published England Royal Society of Chemistry 13.08.2020
Subjects
Colorimetry
Dyes
Fluorescent Dyes - analysis
Lactams - chemistry
Macromolecular Substances - chemistry
Molecular Structure
Optimization
Oxazines - analysis
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Summary:A tetralactam macrocycle acts as a novel supramolecular adjuvant to capture a released resorufin dye and create a higher contrasting yellow/blue color change for enhanced naked eye interpretation of a colorimetric indicator assay. A tetralactam macrocycle captures released resorufin and creates a pair of complementary indicator assay colors that are more easily perceived by the naked eye.
Bibliography:10.1039/d0cc03551c
Electronic supplementary information (ESI) available: Experimental section, synthesis, supplementary figures, modeling data, and references. See DOI
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1359-7345
1364-548X
DOI:10.1039/d0cc03551c