Severe Acute Ischemia of Glans Penis after Achieving Treatment with Only Hyperbaric Oxygen Therapy: A Rare Case Report and Systematic Literature Review

Acute ischemia of the glands is a severe complication after circumcision. We outline the challenging case of a seventeen-year-old boy with glandular ischemia (GI) that appeared shortly after circumcision. Methods: We present a case report and literature review related to glans ischemia, and the comp...

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Published inJournal of personalized medicine Vol. 13; no. 9; p. 1370
Main Authors Hașegan, Adrian, Mihai, Ionela, Bratu, Dan, Bacilă, Ciprian, Roman, Mihai Dan, Mohor, Cosmin Ioan, Teodoru, Adrian, Birsan, Sabrina, Mutu, Cosmin, Chibelean, Călin, Totan, Maria, Grigore, Nicolae, Iancu, Gabriela, Dura, Horatiu, Boicean, Adrian
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 01.09.2023
MDPI
Subjects
Anticoagulants
Bupivacaine
Care and treatment
Case management
Case reports
Circumcision
Complications and side effects
Drugs
Edema
Glans penis
Hematoma
Hemophilia
Hyperbaric oxygen therapy
Iloprost
Infections
Ischemia
Literature reviews
Local anesthesia
Nitrates
Oxygen therapy
Patients
Pediatrics
Penis
Pentoxifylline
Precision medicine
Review
Steroids
Surgery
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Summary:Acute ischemia of the glands is a severe complication after circumcision. We outline the challenging case of a seventeen-year-old boy with glandular ischemia (GI) that appeared shortly after circumcision. Methods: We present a case report and literature review related to glans ischemia, and the complications of circumcision are reviewed. We note that there are very few cases described in the literature. Our patient was successfully treated with hyperbaric oxygen therapy (HBOT) after four days of no positive effect after all medical and surgical treatments written in the literature: Subcutaneous enoxaparin, local application of a glyceryl trinitrate, continuous epidural perfusion, intravenous pentoxifylline, alprostadil, intraoperative drainage, and aspiration with saline solution and epinephrine. Clinical improvement was noted at the first session of HBOT. A number of days after the operation, the penis looked normal and was healing. Complete healing of the penile glans was successfully realized one month after surgery. Conclusion: Based on the review and the case presented, we conclude that HBOT is the treatment of choice for acute ischemia of the penile glans, especially when other treatments do not work.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:2075-4426
2075-4426
DOI:10.3390/jpm13091370