Translational research: A patient-centered approach to bridge the valley of death

• Published in: Cancer Cell Vol. 40; no. 6; pp. 565 - 568
• Main Authors: Thomas, Anish, Desai, Parth, Takahashi, Nobuyuki
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 13.06.2022; Elsevier BV
• Subjects: Animals; Humans; Patient-Centered Care; Translational Research, Biomedical

Animal models have evolved to be a key component of translational research of cancer, and they are now extensively used to test drug candidates, predict drug responses, and essentially drive discovery of cancer biology. However, the model-centric approach has not yielded the expected abundance of tr...