Advances and novel developments in allergic rhinitis

Allergic rhinitis (AR) is an upper airway disease with high prevalence in the world, and therefore needs to be thoroughly investigated and treated accordingly. Although the mechanisms underlying the pathology and treatment of AR have been widely studied, many aspects of AR are still unclear and warr...

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Published inAllergy (Copenhagen) Vol. 75; no. 12; pp. 3069 - 3076
Main Authors Meng, Yifan, Wang, Chengshuo, Zhang, Luo
Format Journal Article
LanguageEnglish
Published Denmark Blackwell Publishing Ltd 01.12.2020
Subjects
Allergic diseases
Allergic rhinitis
Allergies
Biological products
biologics
Humans
Immune system
Immunotherapy
mechanisms
Medical research
Prevalence
Respiratory diseases
Respiratory tract diseases
Rhinitis, Allergic - diagnosis
Rhinitis, Allergic - therapy
treatment
treatment
allergic rhinitis
biologics
mechanisms
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Summary:Allergic rhinitis (AR) is an upper airway disease with high prevalence in the world, and therefore needs to be thoroughly investigated and treated accordingly. Although the mechanisms underlying the pathology and treatment of AR have been widely studied, many aspects of AR are still unclear and warrant further investigations. The purpose of the present review was therefore to report recently published papers, which highlight the novel mechanisms and treatments of AR. These include role of environment, important proteins and cells, and some other factors in the pathogenesis of AR; as well as the role of immunotherapy and biologics in the treatment of AR.
Bibliography:Funding information
Wang and Zhang contributed equally to this work.
This work was supported by grants from the National Natural Science Foundation of China (81900916), Beijing Nova Program (Z201100006820043), Beijing Municipal Administration of Hospitals’ Youth Programme (QML20190208), the Priming Scientific Research Foundation for the Senior Researcher in Beijing TongRen Hospital, Capital Medical University (2017‐YJJ‐GGL‐005), National Key R&D Program of China (2018YFC0116800), the program for Changjiang Scholars and Innovative Research Team (IRT13082), Beijing Scientific and Technological Overall Plan (Z171100000117002), Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support (XMLX201816), Beijing Natural Science Foundation (7194247), CAMS Innovation Fund for Medical Sciences (2019‐I2M‐5‐022), and Beijing Municipal Administration of Hospitals incubating Program (PX20190007).
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ISSN:0105-4538
1398-9995
DOI:10.1111/all.14586