Correlation in retinal thickness and macular retina plus choroidal microcirculation in pediatric myopia

• Published in: Medicine (Baltimore) Vol. 103; no. 30; p. e38915
• Main Authors: Cheng, Fang, Tian, Dan
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 26.07.2024
• Subjects: Adolescent; Child; Choroid - blood supply; Choroid - diagnostic imaging; Choroid - pathology; Female; Humans; Macula Lutea - blood supply; Macula Lutea - diagnostic imaging; Macula Lutea - pathology; Male; Microcirculation - physiology; Myopia - diagnostic imaging; Myopia - pathology; Myopia - physiopathology; Observational Study; Retina - diagnostic imaging; Retina - pathology; Retina - physiopathology; Retinal Vessels - diagnostic imaging; Retinal Vessels - pathology; Retinal Vessels - physiopathology; Tomography, Optical Coherence - methods; myopia; retinal thickness; choroidal microcirculation; retinal microcirculation; pediatric patients
• ISSN: 0025-7974; 1536-5964; 1536-5964
• DOI: 10.1097/MD.0000000000038915

To analyze the relationship in retinal thickness, macula retina and choroidal microcirculation in pediatric patients with myopia. Pediatric patients with high myopia (high myopia group, n = 30, 60 eyes) and pediatric patients with low to moderate myopia (low myopia group, n = 30, 60 eyes) admitted to our hospital from January 2021 to January 2022 were randomly selected as the study subjects. Retinal thickness, the blood density of retina, and the blood density of the choroid were collected in each area of the macula by taking optical coherence tomography (OCT) and OCT angiography (OCTA). Pearson correlation analysis was conducted to compare the results from the 2 groups. Outer retinal thickness showed a weak positive correlation with Superficial vascular complex flow density (SVD) and deep vascular complex flow density (DVD) (P < .05), but no significant correlation with choroidal capillary density (P > .05); inner retinal thickness showed a weak positive correlation with SVD and DVD (P < .05), but no significant correlation with choroidal capillary density (P > .05). In pediatric patients with myopia, there is a positive correlation between the blood flow density of macular retina and retinal thickness, and the retinal thickness will become thinner with increasing myopia.