Prevalence of and Potential Risk Factors for Mild Cognitive Impairment in Community-Dwelling Residents of Beijing

• Published in: Journal of the American Geriatrics Society (JAGS) Vol. 61; no. 12; pp. 2111 - 2119
• Main Authors: Li, Xin, Ma, Chao, Zhang, Junying, Liang, Ying, Chen, Yaojing, Chen, Kewei, Wang, Jun, Zhang, Zhanjun, Wang, Yongyan
• Format: Journal Article
• Language: English
• Published: Hoboken, NJ Blackwell Publishing Ltd 01.12.2013; Wiley-Blackwell; Wiley Subscription Services, Inc
• Subjects: Activities of Daily Living; Aged; Aged, 80 and over; Aging; Biological and medical sciences; Case-Control Studies; China - epidemiology; Cognition & reasoning; Cognitive Dysfunction - epidemiology; Cognitive Dysfunction - etiology; Epidemiology; Female; General aspects; Geriatrics; Humans; leisure activities; lifestyle; Male; Medical sciences; Middle Aged; mild cognitive impairment; Miscellaneous; Neuropsychological Tests; Neuropsychology; Prevalence; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Public health. Hygiene; Public health. Hygiene-occupational medicine; Risk Factors; Surveys and Questionnaires; Beijing China; China, People's Rep., Beijing; Human; risk factors; Prevalence; Cognitive disorder; Activity; Housing; lifestyle; Gerontology; Leisure; At home; Risk factor; Resident (student); Resident; mild cognitive impairment; leisure activities; Elderly; Public health; Geriatrics; Life style
• ISSN: 0002-8614; 1532-5415
• DOI: 10.1111/jgs.12552

Objectives To estimate the prevalence of mild cognitive impairment (MCI) in Beijing, China, and to explore the potential protective and risk factors for MCI. Design Population‐based survey. Setting The Beijing Ageing Brain Rejuvenation Initiative (BABRI). Participants Participants randomly recruited from BABRI (N = 1,211). Measurements Participants underwent a battery of neuropsychological examinations to determine cognitive function and answered a series of personal questions. The prevalence of MCI and its subtypes were computed using Petersen's criteria. Influencing factors for MCI were estimated based on participant medical history, lifestyle, diet, and leisure activities. Results One thousand twenty (aged >55, mean 63.9 ± 6.6; 36.7% male) subjects completed the neuropsychological tests. The overall prevalence of MCI was 15.7%, with single‐domain amnestic, multiple‐domain amnestic, and nonamnestic subtype prevalences of 6.4%, 3.7%, and 5.6%, respectively. Eight hundred sixty‐four subjects were used for the case–control analysis. Hypertension, diabetes mellitus, and cerebrovascular disease were found to be associated with MCI. Healthy diet and greater involvement in physical, intellectual, and social activities were associated with a lower risk of MCI. Conclusion The prevalence of MCI was compatible with that found in previous published reports, and the information on the epidemiology of MCI, especially risk factors, may help to explore therapeutic strategies and preventive approaches to delay conversion to dementia.