Euglycemic Diabetic Ketoacidosis in the ICU: 3 Case Reports and Review of Literature

Diabetic ketoacidosis (DKA) is an acute complication of diabetes mellitus, both type I and type II, as well as other types with diabetes such gestacional diabetes mellitus. It is characterized by blood glucose levels greater than 250 mg/dL and metabolic acidosis (pH < 7.3 and serum bicarbonate &l...

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Published inCase Reports in Critical Care Vol. 2018; no. 2018; pp. 1 - 6
Main Authors Lucero, Pablo, Chapela, Sebastián
Format Journal Article
LanguageEnglish
Published Cairo, Egypt Hindawi Publishing Corporation 2018
Hindawi
Hindawi Limited
Wiley
Subjects
Acidosis
Blood glucose
Carbonates
Case Report
Dapagliflozin
Diabetes mellitus
Diabetic ketoacidosis
Glucose
Hyperglycemia
Insulin glargine
Pregnancy
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Summary:Diabetic ketoacidosis (DKA) is an acute complication of diabetes mellitus, both type I and type II, as well as other types with diabetes such gestacional diabetes mellitus. It is characterized by blood glucose levels greater than 250 mg/dL and metabolic acidosis (pH < 7.3 and serum bicarbonate < 15 mEq/dL) with an increased anion gap and the presence of ketone bodies in the blood or urine. Within this pathology, there is a subgroup of pathologies which are characterized by being present with no signs of hyperglycemia, posing a diagnostic challenge due to the absence of the main sign of the pathology and the diversity of their pathophysiology. In this article, we will present 3 clinical cases with 3 different forms of clinical presentation: a case of DKA in pregnancy, a case of DKA associated with the use of sodium-glucose cotransporter 2 (SGLT-2) inhibitors, and a third case related to sepsis, together with a narrative review of the literature on the topic.
Bibliography:Academic Editor: Chiara Lazzeri
ISSN:2090-6420
2090-6439
DOI:10.1155/2018/1747850