Cognitive dysfunction in first-episode schizophrenia and its correlation with negative symptoms and insight

Background: Cognitive dysfunction in schizophrenia is a well-known feature and can adversely affect the patient participation in treatment and rehabilitation. Studies have shown its relationship to the severity of negative symptoms and level of insight also. Not many Indian studies are available on...

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Published inIndustrial psychiatry journal Vol. 30; no. 2; pp. 310 - 315
Main Authors Bhat, Pookala, Raj, Jitin, Chatterjee, Kaushik, Srivastava, Kalpana
Format Journal Article
LanguageEnglish
Published India Wolters Kluwer India Pvt. Ltd 01.07.2021
Medknow Publications and Media Pvt. Ltd
Medknow Publications & Media Pvt. Ltd
Wolters Kluwer - Medknow
Wolters Kluwer Medknow Publications
Subjects
Care and treatment
Cognition disorders
cognitive dysfunction
insight
negative symptoms
Original
Schizophrenia
India
insight
schizophrenia
Cognitive dysfunction
negative symptoms
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Summary:Background: Cognitive dysfunction in schizophrenia is a well-known feature and can adversely affect the patient participation in treatment and rehabilitation. Studies have shown its relationship to the severity of negative symptoms and level of insight also. Not many Indian studies are available on this in first-episode schizophrenia, and hence, this study was undertaken. Materials and Methods: Eight-five cases of first-episode schizophrenia fulfilling inclusion criteria were included in the study after ethical clearance, informed consent, and stabilization of acute symptoms. All were assessed using psychosocial pro forma, Addenbrooke's Cognitive Examination-III Scale, positive and negative syndrome scale, and schedule for the assessment of insight. Data analysis was done using Statistical Package for Social Sciences Version 20:0. Results: Cognitive dysfunction was seen in 40% of patients. Maximum dysfunction was in the memory domain followed by fluency domain and language domain was relatively well preserved. A significant negative correlation was observed between cognitive function and negative symptoms, but a significant positive correlation was seen with insight. Conclusion: Cognitive dysfunction is present in a significant proportion of schizophrenia in the first episode itself. Early assessment will facilitate appropriate interventions directed at insight and cognitive rehabilitation.
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ISSN:0972-6748
0976-2795
DOI:10.4103/ipj.ipj_107_20