Descriptive epidemiology of IDDM in Hokkaido, Japan: the childhood IDDM Hokkaido registry
Descriptive epidemiology of IDDM in Hokkaido, Japan: the Childhood IDDM Hokkaido Registry. N Matsuura , K Fukuda , A Okuno , S Harada , N Fukushima , A Koike , Y Ito and T Hotsubo Department of Pediatrics, Kitasato University, Sagamihara, Japan. nobumats@med.kitasato-u.ac.jp Abstract OBJECTIVE: To i...
Saved in:
Published in | Diabetes care Vol. 21; no. 10; pp. 1632 - 1636 |
---|---|
Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Alexandria, VA
American Diabetes Association
01.10.1998
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | Descriptive epidemiology of IDDM in Hokkaido, Japan: the Childhood IDDM Hokkaido Registry.
N Matsuura ,
K Fukuda ,
A Okuno ,
S Harada ,
N Fukushima ,
A Koike ,
Y Ito and
T Hotsubo
Department of Pediatrics, Kitasato University, Sagamihara, Japan. nobumats@med.kitasato-u.ac.jp
Abstract
OBJECTIVE: To identify the incidence of IDDM with regard to sex, age, family history of diabetes, season, and 5-year period
of childhood IDDM among children ages 0-14 years from a population-based epidemiological study in Hokkaido, Japan, from 1973
to 1992. RESEARCH DESIGN AND METHODS: Registration of all new IDDM cases in Hokkaido was conducted by the Childhood IDDM Hokkaido
Registry Study Group from 1973 to 1992. The cases were selected from among 1) patients who were admitted to the member hospitals
of the study group, 2) patients who answered a questionnaire distributed to hospitals and diabetic clinics throughout Hokkaido,
and 3) patients whose cases were recorded in free-treatment medical records of urban and rural districts. The case ascertainment
rate was estimated to be 100%. Differences in incidence with regard to sex, age, family history of diabetes, season, and year
period were analyzed by the Poisson regression analysis by GENMOD. RESULTS: During the 20-year period studied, 396 cases (181
boys, 215 girls) of abrupt-onset IDDM were registered. Statistically significant differences in annual incidence were found
according to sex (female), age (8-14 years), history (having no diabetes in family), season (spring), and 5-year period. CONCLUSIONS:
This is the first population-based, long-term epidemiological study of childhood IDDM from Japan. We observed a significantly
higher annual incidence (per 100,000/year) of IDDM in female subjects (1.81), older age-groups (2.25 for 8-14 years), subjects
with no family history of diabetes (1.26), diabetes onset in the spring (2.20), and an increased trend over the 20 years.
In addition, the heterogeneity of IDDM among Japanese children needs to be elucidated. |
---|---|
Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0149-5992 1935-5548 |
DOI: | 10.2337/diacare.21.10.1632 |