Association between autosomal dominant polycystic kidney disease and autoimmune diseases: A simple coincidence or more?

• Published in: Saudi journal of kidney diseases and transplantation Vol. 28; no. 2; pp. 441 - 444
• Main Authors: Barbouch, Samia, Hajji, Meriam, Jaziri, Fatima, Harzallah, Amel, Fellah, Eya, Hedri, Hafedh, Hamida, Fethi Ben, Abdelghani, Khaoula Ben, Abdallah, Taieb Ben
• Format: Journal Article
• Language: English
• Published: Saudi Arabia Medknow Publications and Media Pvt. Ltd 01.03.2017; Medknow Publications & Media Pvt. Ltd; Wolters Kluwer Medknow Publications
• Subjects: Abdomen; Adult; Anemia; Autoimmune diseases; Biopsy; Blood pressure; Cysts; Edema; Family medical history; Female; Hospitals; Humans; Hypertension; Immunosuppressive Agents - therapeutic use; Kidney diseases; Laboratories; Lupus; Lupus Nephritis - complications; Lupus Nephritis - diagnosis; Lupus Nephritis - drug therapy; Lupus Nephritis - physiopathology; Magnetic Resonance Imaging; Medicine; Nephrology; Nephrotic Syndrome - diagnosis; Nephrotic Syndrome - drug therapy; Nephrotic Syndrome - etiology; Nephrotic Syndrome - physiopathology; Patients; Polycystic Kidney, Autosomal Dominant - complications; Polycystic Kidney, Autosomal Dominant - diagnosis; Polycystic Kidney, Autosomal Dominant - drug therapy; Polycystic Kidney, Autosomal Dominant - physiopathology; Proteins; Proteinuria - etiology; Scleroderma; Scleroderma, Systemic - complications; Scleroderma, Systemic - diagnosis; Scleroderma, Systemic - drug therapy; Scleroderma, Systemic - physiopathology; Treatment Outcome; Ultrasonic imaging; Urine; Urological Agents - therapeutic use; Veins & arteries; Vitamin E; Young Adult
• ISSN: 1319-2442; 2320-3838
• DOI: 10.4103/1319-2442.202772

All these data were in keeping with LN. [...]it was possible to make a diagnosis of systemic lupus erythematosus (SLE) with both renal and cerebrovascular involvement. The treatment included captopril, prednisolone, diltiazem and Vitamin E. Two years after, there was normalization of blood pressure, regression of proteinuria, and decrease of the serum creatinine (111 μmol/L) with eDFG of 49 mL/min. Since that, she was only followed up for two years then she never consulted. [...]our patient presented a posterior arachnoids cyst. [...]ADPKD may remain asymptomatic for a longtime[2] as in both of our cases. [...]ultrasonography is the procedure of choice in the workup of patients with ADPKD.