Allergic transfusion reaction caused by the shrimp allergen of donor blood: A case report

• Published in: Transfusion and apheresis science Vol. 50; no. 1; pp. 68 - 70
• Main Authors: Gao, Lingbao, Sha, Yayun, Yuan, Keyu, Ling, Liu, Ai, Dongqin, Ying, Huang, Xiu, Chen, Peng, Hailin, Chen, Yabao, Li, Zhu
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.02.2014
• Subjects: Allergens - blood; Allergic transfusion reactions; Animals; Blood Donors; Food Hypersensitivity; Health technology assessment; Hematology, Oncology and Palliative Medicine; Humans; IgA; IgE; Immunoglobulin A - blood; Immunoglobulin A - immunology; Immunoglobulin E - blood; Immunoglobulin E - immunology; Male; Middle Aged; Nephelometry and Turbidimetry; Penaeidae; Shrimp; sIgE; Transfusion Reaction - diagnosis; Vegetarian; sIgE; IgA; Allergic transfusion reactions; IgE; Vegetarian; Shrimp
• ISSN: 1473-0502; 1878-1683
• DOI: 10.1016/j.transci.2013.09.016

Abstract Objective The purpose of this report is to analyze the cause of allergic transfusion reaction. Methods The methods of immunoblot and immunonephelometry were applied to detect the levels of the immunoglobulins of IgA (Immunoglobulin A) and IgE (Immunoglobulin E) and the level of sIgE (specific Immunoglobulin E) to shrimp allergen both in the patient’s pre and post transfusion blood samples, respectively. Results After transfusion, The level of sIgE to shrimp showed “increase” corresponding to the concentration of 0.70–3.5 IU/ml. Conclusion The allergic transfusion reaction was very likely caused by passive transfer of shrimp antigen to the patient allergic to shrimp.