Recombinant cytokines for controlling mycobacterial infections

Knowing how mycobacteria exploit host cytokines to survive and which cytokines have important roles in host defense against mycobacteria should allow the use of these molecules in the treatment of mycobacterial infections. Both interleukin 2 and interferon γ have been used to treat patients with lep...

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Bibliographic Details
Published inTrends in Microbiology Vol. 3; no. 1; pp. 22 - 27
Main Authors Bermudez, Luiz E., Kaplan, Gilla
Format Book Review Journal Article
LanguageEnglish
Published England Elsevier Ltd 1995
Subjects
AIDS/HIV
Cytokines - administration & dosage
Cytokines - therapeutic use
Humans
Leprosy - prevention & control
Mycobacterium avium
Mycobacterium avium-intracellulare Infection - prevention & control
Mycobacterium Infections - prevention & control
Recombinant Proteins - administration & dosage
Recombinant Proteins - therapeutic use
Tuberculosis - prevention & control
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Summary:Knowing how mycobacteria exploit host cytokines to survive and which cytokines have important roles in host defense against mycobacteria should allow the use of these molecules in the treatment of mycobacterial infections. Both interleukin 2 and interferon γ have been used to treat patients with leprosy, and granulocyte-macrophage colony-stimulating factor is presently being administered to AIDS patients infected with Mycobacterium avium.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ObjectType-Review-3
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ISSN:0966-842X
1878-4380
DOI:10.1016/S0966-842X(00)88864-2