Synthesis and properties of new biotin compounds containing hexyltriethylene glycol chain

The synthesis of a new halogenide containing hexyltriethylene glycol chain functionalized with biotin is reported. The general possibility of this linker to use as the building block for biotinylated compounds syntheses is demonstrated. Two biotinylated esters with different properties for useful su...

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Bibliographic Details
Published inCentral European journal of chemistry Vol. 10; no. 1; pp. 113 - 120
Main Authors Matijoška, Algirdas, Charkova, Tatjana, Kuodis, Zenonas, Voiciuk, Vladislava, Eicher-Lorka, Olegas
Format Journal Article
LanguageEnglish
Published Heidelberg SP Versita 01.02.2012
Versita
De Gruyter
Subjects
Biochemistry
Biological and Medical Physics
Biophysics
Biotinylated esters
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Fluorescent probe
Geochemistry
Research Article
Self-assembled monolayers
Stilbazolium
Stilbazolium
Self-assembled monolayers
Biotinylated esters
Fluorescent probe
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Summary:The synthesis of a new halogenide containing hexyltriethylene glycol chain functionalized with biotin is reported. The general possibility of this linker to use as the building block for biotinylated compounds syntheses is demonstrated. Two biotinylated esters with different properties for useful surface modification and as fluorescence probes for proteins marking were synthesized. The properties of mentioned compounds were investigated by using surface plazmon resonance ellypsometry and fluorescence spectroscopy.
ISSN:1895-1066
2391-5420
1644-3624
2391-5420
DOI:10.2478/s11532-011-0113-8