Surgical Management of Vascular Graft Infection in Severely Ill Patients by Partial Resection of the Infected Prosthesis

• Published in: European journal of vascular and endovascular surgery Vol. 33; no. 5; pp. 610 - 613
• Main Authors: Mirzaie, M, Schmitto, J.D, Tirilomis, T, Fatehpur, S, Liakopoulos, O.J, Teucher, N, Dörge, H, Schöndube, F.A
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.05.2007
• Subjects: Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal - epidemiology; Aortic Aneurysm, Abdominal - surgery; Blood Vessel Prosthesis - adverse effects; Blood Vessel Prosthesis Implantation; Comorbidity; Debridement; Female; Humans; Male; Middle Aged; Prosthesis infection; Prosthesis-Related Infections - epidemiology; Prosthesis-Related Infections - surgery; Surgery; Surgical management in severely ill patients; Surgical Wound Dehiscence; Vascular graft infection; Vascular graft infection; Prosthesis infection; Surgical management in severely ill patients
• ISSN: 1078-5884; 1532-2165
• DOI: 10.1016/j.ejvs.2006.11.042

Introduction In the presented retrospective study, we report on our results with partial resection of infected prosthetic grafts after aorto-bifemoral graft placement in eight male and three female patients. Methods In all 11 patients clinical signs of infection were observed and bacteriological cultures were positive. Three patients underwent immediate surgery for perforation of an aneurysm at the distal anastomosis, eight patients underwent elective surgery. In all cases silver-coated Dacron prostheses were implanted. Assessment of outcome was based on survival, limb salvage, persistent or recurrent infection, and prosthetic graft patency. Results In two cases, a partial wound dehiscence occurred which was treated with ambulant Vacuseal dressings for 16 and 21 days until secondary wound healing was achieved. In eight patients systemic markers of inflammation completed normalised within nine days. Follow-up CT-scans failed to demonstrate any signs of recurrent infection or peri-graft fluid collections. Patients were treated with specific antibiotic therapy for no more than three months. Post-operative bacteriological cultures were negative in all patients. The mean follow-up was 2.5 ± 0.5 yrs. During follow-up, none of the patients died and there were no amputations. Conclusion Despite only partial resection of the infected prostheses, the reported surgical procedure offers good results. This approach maybe particularly suitable for the treatment of elderly patients with prosthesis infections.