The Neonatal Connectome During Preterm Brain Development

• Published in: Cerebral cortex (New York, N.Y. 1991) Vol. 25; no. 9; pp. 3000 - 3013
• Main Authors: van den Heuvel, Martijn P., Kersbergen, Karina J., de Reus, Marcel A., Keunen, Kristin, Kahn, René S., Groenendaal, Floris, de Vries, Linda S., Benders, Manon J.N.L.
• Format: Journal Article
• Language: English
• Published: United States Oxford University Press 01.09.2015
• Subjects: Adult; Brain - blood supply; Brain - growth & development; Brain - pathology; Connectome; Diffusion Magnetic Resonance Imaging; Female; Gestational Age; Humans; Image Processing, Computer-Assisted; Infant, Newborn; Magnetic Resonance Imaging; Male; Neural Pathways - blood supply; Neural Pathways - growth & development; Neural Pathways - pathology; Oxygen - blood; Premature Birth - pathology; White Matter - blood supply; White Matter - growth & development; White Matter - pathology; Young Adult; neonatal; structural connectivity; connectome; development; functional connectivity

The human connectome is the result of an elaborate developmental trajectory. Acquiring diffusion-weighted imaging and resting-state fMRI, we studied connectome formation during the preterm phase of macroscopic connectome genesis. In total, 27 neonates were scanned at week 30 and/or week 40 gestation...