Imaging characteristics of toxoplasmosis encephalitis after bone marrow transplantation : report of two cases and review of the literature

• Published in: Neuroradiology Vol. 48; no. 2; pp. 84 - 89
• Main Authors: MUELLER-MANG, C, MANG, T. G, KALHS, P, THURNHER, M. M
• Format: Journal Article
• Language: English
• Published: Berlin Springer 01.02.2006; Springer Nature B.V
• Subjects: Adult; Biological and medical sciences; Bone marrow; Bone Marrow Transplantation - adverse effects; Brain; Case studies; Diffusion Magnetic Resonance Imaging; Encephalitis; Fatal Outcome; Female; Fundamental and applied biological sciences. Psychology; Humans; Immunocompromised Host; Investigative techniques, diagnostic techniques (general aspects); Male; Medical sciences; Middle Aged; Nervous system; NMR; Nuclear magnetic resonance; Opportunistic Infections - diagnosis; Opportunistic Infections - parasitology; Parasitic diseases; Perception; Psychology. Psychoanalysis. Psychiatry; Psychology. Psychophysiology; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Tomography; Tomography, X-Ray Computed; Toxoplasmosis, Cerebral - diagnosis; Transplants & implants; Vision; Encephalitis; Brain; Protozoal disease; Nervous system diseases; Radiodiagnosis; Bone marrow transplantation; Transplantation; Parasitosis; Review; Nuclear magnetic resonance imaging; Cerebral disorder; Infection; Case study; Magnetic resonance imaging; Toxoplasmosis; Central nervous system disease; Bone marrow
• ISSN: 0028-3940; 1432-1920
• DOI: 10.1007/s00234-005-0018-3

Toxoplasmosis encephalitis is a severe, but often misdiagnosed complication in patients after bone marrow transplantation (BMT). We describe the unique computed tomography (CT) and magnetic resonance (MR) imaging features of cerebral toxoplasmosis in two bone marrow recipients and compare them to the cases in the literature. To our knowledge, this is the first report analyzing the appearance of cerebral toxoplasmosis on diffusion-weighted MR imaging (DWI).