The role of the neutrophil and phagocytosis in infection caused by Helicobacter pylori

Recent advances in our understanding of Helicobacter pylori-phagocyte interactions indicate that these organisms actively modulate phagocyte function in order to retard phagocytosis, while simultaneously inducing a strong respiratory burst. The central players in this dynamic include H. pylori neutr...

Full description

Saved in:
Bibliographic Details
Published inCurrent opinion in infectious diseases Vol. 14; no. 3; p. 273
Main Author Allen, L A
Format Journal Article
LanguageEnglish
Published United States 01.06.2001
Subjects
Helicobacter Infections - immunology
Helicobacter Infections - microbiology
Helicobacter pylori - pathogenicity
Humans
Neutrophils - immunology
Neutrophils - microbiology
Phagocytosis - immunology
Online AccessGet more information

Cover

More Information
Summary:Recent advances in our understanding of Helicobacter pylori-phagocyte interactions indicate that these organisms actively modulate phagocyte function in order to retard phagocytosis, while simultaneously inducing a strong respiratory burst. The central players in this dynamic include H. pylori neutrophil activating protein and factors that are associated with the cag pathogenicity island type IV secretion apparatus. Additionally, catalase, alkyl hydroperoxide reductase, and factors that are unique to type I strains allow bacteria to resist phagocytic killing.
ISSN:0951-7375
DOI:10.1097/00001432-200106000-00005