A comparison of the results of monolayer versus smear cytopreparatory techniques for fine-needle aspiration in 100 consecutive patients undergoing thyroidectomy: a surgeon's perspective

To compare thyroid fine-needle aspiration (FNA) using monolayer (MT) versus conventional smear (CS) cytopreparatory techniques with final histology. Retrospective review of 100 consecutive thyroidectomies. Setting Tertiary care university affiliated medical center. 26% of MT aspirates were inadequat...

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Bibliographic Details
Published inOtolaryngology-head and neck surgery Vol. 131; no. 6; p. 964
Main Author Witt, Robert L
Format Journal Article
LanguageEnglish
Published England 01.12.2004
Subjects
Biopsy, Fine-Needle
Cytological Techniques - methods
Humans
Predictive Value of Tests
Preoperative Care
Retrospective Studies
Thyroid Nodule - pathology
Thyroid Nodule - surgery
Thyroidectomy
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Summary:To compare thyroid fine-needle aspiration (FNA) using monolayer (MT) versus conventional smear (CS) cytopreparatory techniques with final histology. Retrospective review of 100 consecutive thyroidectomies. Setting Tertiary care university affiliated medical center. 26% of MT aspirates were inadequate compared with 3% of CS aspirates (P < 0.05). The negative predictive values for MT and CS were 86% and 100%, respectively. The positive predictive values for MT and CS were 69% and 90%, respectively. Fewer inadequate specimens will be obtained with CS than with MT. A clinician performing FNA can obtain adequate specimens at a rate comparable to that of a hospital-based cytopathologist. CS provides greater assurance to the patient and the surgeon that a thyroid nodule with a FNA interpreted as benign can be observed. A higher percentage of patients with malignant tumor will receive thyroidectomy with the use of CS technique for FNA. B-3.
ISSN:0194-5998
DOI:10.1016/j.otohns.2004.07.004