Etiology of reactive arthritis in Pan paniscus, P. troglodytes troglodytes, and P. troglodytes schweinfurthii

• Published in: American journal of primatology Vol. 66; no. 3; pp. 219 - 231
• Main Authors: Rothschild, Bruce M., Rühli, Frank J.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.07.2005; Wiley-Liss
• Subjects: Africa South of the Sahara; Animals; Ape Diseases - etiology; Ape Diseases - pathology; arthritis; Arthritis, Reactive - etiology; Arthritis, Reactive - pathology; Arthritis, Reactive - veterinary; Biological and medical sciences; Biological anthropology; Bone and Bones - pathology; chimpanzee; Chimpanzees; Environment; Etiology; Fundamental and applied biological sciences. Psychology; Joints - pathology; Pan paniscus; Pan troglodytes; Paniscus; Pathology; Primate biology; primate infectious-agent diarrhea; Primates; Primatology; Sexual Behavior, Animal - physiology; Shigella; Skeleton and joints; Species Specificity; spondyloarthropathy; Troglodytes; Troglodytes troglodytes; Vertebrates: osteoarticular system, musculoskeletal system; Yersinia; Africa South of the Sahara; Interspecific comparison; Pan paniscus; Diarrhea; Arthritis; Pan troglodytes; Joint; Osteoarticular system; primate infectious-agent diarrhea; Vertebrata; Mammalia; Etiology; spondyloarthropathy; Primates; Simioidea; Bacteria; chimpanzee; Aves; Shigella; Enterobacteriaceae; Field study
• ISSN: 0275-2565; 1098-2345
• DOI: 10.1002/ajp.20140

The character of arthritis has not received the same attention in Pan paniscus as it has in P. troglodytes. Reactive arthritis (a form of spondyloarthropathy) in the latter has been considered to be either a sexually transmitted or an infectious‐agent diarrhea‐related disorder. The unique sexual promiscuity of P. paniscus enables us to distinguish between those hypotheses. The macerated skeletons of 139 adult P. paniscus, P. troglodytes troglodytes, and P. troglodytes schweinfurthii were macroscopically analyzed for osseous and articular pathologies. The sex of the animal was recorded at the time of acquisition. Twenty‐one percent of the P. paniscus, 28% of the P. t. troglodytes, and 27% of the P. t. schweinfurthii specimens had peripheral and central joint erosive disease characteristic of spondyloarthropathy. Subchondral pauciarticular distribution and reactive new bone clearly distinguish this disease from rheumatoid arthritis, osteoarthritis, and direct bone/joint infection. The fact that P. paniscus and P. t. troglodytes were similar in terms of disease frequency makes the notion of sexual transmission unlikely. While the frequencies of spondyloarthropathy were indistinguishable among all species/subspecies studied, the patterns of joint involvement were disparate. The Pan paniscus and P. t. troglodytes home ranges are geographically separate. We assessed possible habitat factors (e.g., exposure to specific infectious agents of diarrhea) by comparing P. paniscus and P. t. troglodytes with P. t. schweinfurthii. The latter shared similar patterns and habitats (separated by the Congo River) with P. paniscus. The explanation offered for habitat‐specific patterns is differential bacterial exposure–most likely Shigella or Yersinia in P. paniscus and P. t. schweinfurthii. Am. J. Primatol. 66:219–231, 2005. © 2005 Wiley‐Liss, Inc.