Surgical treatment of cardiac lipoma: 20 years' experience in a single center

• Published in: Chinese medical journal Vol. 136; no. 5; pp. 565 - 570
• Main Authors: Li, Linlin, Meng, Jian, Zhou, Xingtong, Liu, Chang, Guo, Hongwei, Fan, Hongguang
• Format: Journal Article
• Language: English
• Published: China Lippincott Williams & Wilkins Ovid Technologies 05.03.2023; Lippincott Williams & Wilkins; Wolters Kluwer
• Subjects: Adipocytes; Asymptomatic; Autopsies; Body mass index; Cardiac arrhythmia; Cardiovascular disease; Diabetes; Heart; Heart Neoplasms - surgery; Hospitals; Humans; Hyperlipidemia; Hypertension; Hypothyroidism; Lipoma - pathology; Magnetic resonance imaging; Original; Patients; Pericardium; Prognosis; Retrospective Studies; Surgery; Thyroid cancer; Tomography; Tumors; Vena Cava, Superior - pathology; New York; United States > US
• ISSN: 2542-5641; 0366-6999; 2542-5641
• DOI: 10.1097/CM9.0000000000002585

Primary cardiac lipoma is very rare, and no consensus has been developed regarding its ideal treatment strategy. This study reviewed the surgical treatment of cardiac lipomas in 20 patients over 20 years. Twenty patients with cardiac lipomas were treated at Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College from January 1, 2002, to January 1, 2022. The patients' clinical data and pathological reports were retrospectively analyzed, and the follow-up with a range of 1 year to 20 years was conducted. The cardiac lipomas were located in the right atrium (RA) or superior vena cava (SVC) in seven patients (35%) (RA in six patients and SVC in one patient), left ventricle in eight patients (40%) (left ventricular chamber in four patients and left ventricular subepicardium and myocardium in four patients), right ventricle in three patients (15%) (right ventricular chamber in one patient and right ventricular subepicardial layer and myocardium in two patients), subepicardial interventricular groove in one patient (5%), and pericardium in one patient (5%). Complete resection was achieved in 14 patients (70%), including seven patients with lipomas in the RA or SVC. Incomplete resection occurred in six patients (30%) with lipomas in the ventricles. No perioperative deaths occurred. Long-term follow-up was conducted for 19 patients (95%), including two (10%) who died. Both patients who died had lipomas incompletely resected due to ventricles involvement, and preoperative malignant arrhythmias persisted post-operatively. The complete resection rate was high, and the long-term prognosis was satisfactory in patients with cardiac lipomas that did not involve the ventricle. The complete resection rate was low in patients with cardiac lipomas in ventricles; and complications, including malignant arrhythmia, were common. Failure of complete resection and post-operative ventricular arrhythmia are correlated with post-operative mortality.