Pseudotumor presentation of intracerebral tuberculomas

Diagnosis of tuberculoma is difficult because of its tumorlike aspects. This report describes the case of a male who displayed a hemiplegia revealing an intracranial mass. Neuroimaging was consistent with a glioblastoma; however, the definite diagnosis was a tuberculoma. Clinical features of tubercu...

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Published inSouthern medical journal (Birmingham, Ala.) Vol. 98; no. 4; pp. 489 - 491
Main Authors CHANET, Valérie, BAUD, Olivier, DEFFOND, Didier, ROMASZKO, Jean-Pierre, BEYTOUT, Jean
Format Journal Article
LanguageEnglish
Published Hagerstown, MD Lippincott Williams & Wilkins 01.04.2005
Southern Medical Association
Subjects
Bacterial diseases
Biological and medical sciences
Brain Neoplasms - diagnosis
Brain tumors
Case studies
Diagnosis, Differential
General aspects
Glioblastoma - diagnosis
Human bacterial diseases
Humans
Infectious diseases
Male
Medical sciences
Middle Aged
Pseudotumor Cerebri - diagnosis
Pseudotumor Cerebri - etiology
Tuberculoma, Intracranial - diagnosis
Tuberculosis and atypical mycobacterial infections
United States
Infection
Medicine
Pseudotumor
Tuberculosis
Bacteriosis
Tumor
Tuberculoma
Mycobacterial infection
Intracerebral
Encephalon
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Summary:Diagnosis of tuberculoma is difficult because of its tumorlike aspects. This report describes the case of a male who displayed a hemiplegia revealing an intracranial mass. Neuroimaging was consistent with a glioblastoma; however, the definite diagnosis was a tuberculoma. Clinical features of tuberculomas are nonspecific. Even though the neuroimaging features are sensitive, they are much less specific, with variability related to the tuberculoma course. Investigations leading to the diagnosis are histologic analysis showing a granuloma with or without caseating necrosis, and the microbiologic identification of Mycobacterium tuberculosis. Every intracranial tumor with malignant radiologic and clinical appearance must evoke a suspicion for tuberculoma.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
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ISSN:0038-4348
1541-8243
DOI:10.1097/01.SMJ.0000152544.47644.25