A recent overview on the synthesis of 1,4,5-trisubstituted 1,2,3-triazoles

Diverse strategies for the efficient and attractive synthesis of a wide variety of relevant 1,4,5-trisubstituted 1,2,3-triazole molecules are reported. The synthesis of this category of diverse fully functionalized 1,2,3-triazoles has become a necessary and unique research subject in modern syntheti...

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Bibliographic Details
Published inBeilstein journal of organic chemistry Vol. 17; no. 1; pp. 1600 - 1628
Main Authors Shiri, Pezhman, Amani, Ali Mohammad, Mayer-Gall, Thomas
Format Journal Article
LanguageEnglish
Published Frankfurt am Main Beilstein-Institut zur Föerderung der Chemischen Wissenschaften 13.07.2021
Beilstein-Institut
Subjects
1,4,5-trisubstituted 1,2,3-triazoles
[3 + 2]‐cycloaddition
Azide
azides
Catalysis
Chemistry
click reaction
fully functionalized 1,2,3-triazoles
n-containing heterocycles
Review
Triazoles
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Summary:Diverse strategies for the efficient and attractive synthesis of a wide variety of relevant 1,4,5-trisubstituted 1,2,3-triazole molecules are reported. The synthesis of this category of diverse fully functionalized 1,2,3-triazoles has become a necessary and unique research subject in modern synthetic organic key transformations in academia, pharmacy, and industry. The current review aims to cover a wide literature survey of numerous synthetic strategies. Recent reports (2017–2021) in the field of 1,4,5-trisubstituted 1,2,3-triazoles are emphasized in this current review.
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ISSN:1860-5397
2195-951X
1860-5397
DOI:10.3762/bjoc.17.114